Home
Currency:USD
Language: en

ED RX Medications

0
You have no items in your shopping cart.

0

Currency: USD
Language: English

Welcome to our online pharmacy!

Vega Extra Cobra (sildenafil citrate)

Vega Extra Cobra (sildenafil citrate)

$ 1.02 per pill

Quick Overview

Since the combined use of Cobra Vega Extra Strong 120 Mg and α-blockers can lead to symptomatic hypotension in some sensitive patients, Cobra Vega Extra Strong 120 Mg should be used with caution in patients taking α-blockers (see "Interaction"). To minimize the risk of postural hypotension in patients taking α-blockers, the drug Cobra Vega Extra Strong 120 Mg should be started only after achieving stabilization of hemodynamic parameters in these patients. It should also consider reducing the initial dose of Cobra Vega Extra Strong 120 Mg (see. "Dosage and administration"). The doctor should inform patients about what actions should be taken in case of symptoms of postural hypotension.

Vega Extra Cobra® (Signature)

Vega Extra Cobra (Sildenafil citrate) 120 mg

Vega Extra Cobra
Sildenafil citrate
120 mg × 180 pills
$ 193.90 $ 183.95
$ 1.02 per pill
Buy
Vega Extra Cobra
Sildenafil citrate
120 mg × 120 pills
$ 160.90 $ 151.95
$ 1.27 per pill
Buy
Vega Extra Cobra
Sildenafil citrate
120 mg × 90 pills
$ 145.90 $ 137.95
$ 1.53 per pill
Buy
Vega Extra Cobra
Sildenafil citrate
120 mg × 60 pills
$ 115.90 $ 109.95
$ 1.83 per pill
Buy
Vega Extra Cobra
Sildenafil citrate
120 mg × 30 pills
$ 67.90 $ 63.95
$ 2.13 per pill
Buy
Vega Extra Cobra
Sildenafil citrate
120 mg × 20 pills
$ 49.90 $ 46.95
$ 2.35 per pill
Buy
Vega Extra Cobra
Sildenafil citrate
120 mg × 10 pills
$ 27.90 $ 25.95
$ 2.59 per pill
Buy

Information

Side effect

The most common side effects were headache and tides.

Usually the side effects of Vega Extra 120 Mg are mild or moderate and are transient.

Studies using a fixed dose have shown that the frequency of some adverse events increases with increasing dose.

The frequency of adverse reactions is presented in the following classification: very often — ≥10%; often — ≥1% and <10%; infrequently — ≥0.1% and <1%; rarely — ≥0.01% and <0.1%; very rarely — <0.01%; frequency unknown — cannot be determined based on available data.

Co side of the immune system: infrequently — hypersensitivity reactions (including skin rash), allergic reactions.

On the part of the organ of vision: often — blurred vision, blurred vision, cyanopsia; rarely, eye pain, photophobia, photopsia, chromatopsia, eye redness/injection of the sclera, changing the brightness of cvetovete, mydriasis, conjunctivitis, hemorrhage in the tissue of the eye, cataract, a disorder of the lacrimal apparatus; rarely — swelling of the eyelids and adjacent tissues, a feeling of dryness in the eyes, the presence of iridescent circles in the field of view around the light source, increased fatigue of the eyes, vision of objects in yellow (xanthopsia), vision of objects in red (erythropsia), conjunctival hyperemia, irritation of the mucous membrane of the eyes, unpleasant sensations in the eyes; the frequency is unknown — NPINZN, occlusion of retinal veins, visual field defect, diplopia*, temporary vision loss or decreased visual acuity, increased IHD, edema retina, retinal vascular disease, vitreous detachment/vitreal traction.

On the part of the organ of hearing: infrequent — a sudden decrease or loss of hearing, tinnitus, pain in the ears.

From the CCC: often — tides; infrequently — tachycardia, palpitations, decreased blood PRESSURE, increased heart rate, unstable angina, AV-blockade, myocardial infarction, cerebral thrombosis, cardiac arrest, heart failure, deviations in ECG readings, cardiomyopathy; rarely — atrial fibrillation, sudden cardiac death*, ventricular arrhythmia*.

The blood and lymphatic system: rarely — anemia, leukopenia.

On the part of metabolism and nutrition: infrequently — a feeling of thirst, swelling, gout, uncompensated diabetes, hyperglycemia, peripheral edema, hyperuricemia, hypoglycemia, hypernatremia.

From the respiratory system: often — nasal congestion; infrequent — nosebleeds, rhinitis, asthma, dyspnea, laryngitis, pharyngitis, sinusitis, bronchitis, increased volume of sputum, increased cough; rarely — a feeling of tightness in the throat, dryness of the nasal mucosa, swelling of the nasal mucosa.

From the digestive tract: often — nausea, dyspepsia; uncommon — GERD, vomiting, pain in the abdomen, dryness of the mucous membrane of the mouth, glossitis, gingivitis, colitis, dysphagia, gastritis, gastroenteritis, esophagitis, stomatitis, rejection of liver function tests from normal, rectal bleeding; rarely, hypesthesia of the mucous membrane of the oral cavity.

On the part of the musculoskeletal system: often — back pain; infrequently — myalgia, pain in the limbs, arthritis, arthrosis, tendon rupture, tenosynovitis, bone pain, myasthenia gravis, synovitis.

From the genitourinary system: infrequently — cystitis, nicturia, breast enlargement, urinary incontinence, hematuria, ejaculation disorders, genital edema, anorgasmia, hematospermia, damage to the tissues of the penis; rarely — prolonged erection and/or priapism.

From the Central and peripheral nervous system: very often — headache; often — dizziness; infrequently — drowsiness, migraine, ataxia, hypertension, neuralgia, neuropathy, paresthesia, tremor, vertigo, symptoms of depression, insomnia, unusual dreams, increased reflexes, hypesthesia; rarely — convulsions*, repeated convulsions*, fainting.

On the part of the skin and subcutaneous tissues: infrequently — skin rash, urticaria, herpes simplex, itching, sweating, skin ulceration, contact dermatitis, exfoliative dermatitis; the frequency is unknown — Stevens-Johnson syndrome, toxic epidermal necrolysis.

Other: infrequently — a feeling of heat, swelling of the face, photosensitivity reaction, shock, asthenia, fatigue, pain of various localization, chills, accidental falls, chest pain, accidental injuries; rarely — irritability.

Clinical data

In a placebo-controlled cross-examination of patients with proven early age macular degeneration (n=9), Vega Extra 120 Mg was well tolerated at a single dose of 100 mg. There were no clinically significant changes in vision evaluated by special visual tests (visual acuity, Amsler lattice, color perception, color simulation, Humphrey perimeter and photostress).

Efficiency. The efficacy and safety of Vega Extra 120 Mg were evaluated in 21 randomized double-blind placebo-controlled studies lasting up to 6 months in 3000 patients from 19 to 87 years with erectile dysfunction of different etiology (organic, psychogenic or mixed). The efficacy of the drug was evaluated globally using an erection diary, an international erectile function index (validated questionnaire on the state of sexual function) and a partner survey.

The effectiveness of Vega Visa, defined as the ability to achieve and maintain an erection sufficient for satisfactory sexual intercourse, has been demonstrated in all studies and confirmed in long-term studies lasting 1 year. In studies with the use of fixed-dose proportion of patients reporting that treatment improved their erections were 62% (dose of Vega Extra Cobra 25 mg), 74% (dose Cobra Vega Extra 50 mg) and 82% (dose Vega Cobra 120 Mg 100 mg) compared to 25% in the placebo group. Analysis of the international index of erectile function showed that in addition to improving erection treatment Vega Extra 120 Mg also increased the quality of orgasm, allowing to achieve satisfaction from sexual intercourse and overall satisfaction.

According to the generalized data, 59% of patients with diabetes, 43% of patients who underwent radical prostatectomy and 83% of patients with spinal cord injuries (against 16, 15 and 12% in the placebo group, respectively) were reported to have improved erection in the treatment of Vega Extra 120.

Pharmacokinetics

Influence of Sildenafil Tablets Vega Extra Cobra on other drugs

Sildenafil Vega Extra 120 is a weak inhibitor of cytochrome P450 — 1A2, 2C9, 2C19, 2D6, 2E1 and 3A4 ISOENZYMES (IC50 >150 µmol). When taking Vega Extra 120 Mg in recommended doses, its Cmax is about 1 µmol, so it is unlikely that Vega Visa can affect the clearance of the substrates of these isoenzymes.

Vega Extra Cobra 130 Mg increases the hypotensive effect of nitrates both with long-term use of the latter, and with their appointment for urgent indications. In this regard, the use of Vega Extra 120 Mg in combination with nitrates or nitric oxide donators is contraindicated. While taking α-adrenoblocker doxazosin (4 and 8 mg) and Vega Cobra (25, 50 and 100 mg) in patients with benign prostate hyperplasia with stable hemodynamics, the average additional decrease in sad/dad in the supine position was 7/7, 9/5 and 8/4 mm Hg.article, respectively, while in the standing position — 6/6, 11/4 mmHg, and 4/5.art. respectively. Reported rare cases of symptomatic postural hypotension in such patients, manifested in the form of dizziness (without fainting). In some sensitive patients receiving α-blockers, simultaneous use of Vega Extra 120 Mg can lead to symptomatic hypotension.

There were no signs of significant interaction with tolbutamide (250 mg) or warfarin (40 mg), which are metabolized by CYP2C9 isoenzyme.

Vega Extra 120 Mg (100 mg) has no effect on the pharmacokinetics of the HIV protease inhibitor, saquinavir, which is a substrate of CYP3A4 isoenzyme, at its constant level in the blood.

The simultaneous use of Vega Extra 120 Mg at equilibrium (80 mg 3 times a day) leads to an increase in the AUC and Cmax of bosentan (125 mg 2 times a day) by 49.8 and 42%, respectively.

Vega Extra 120 Mg (50 mg) does not cause an additional increase in bleeding time when taking acetylsalicylic acid (150 mg).

Vega Extra 120 Mg (50 mg) does not increase the hypotensive effect of alcohol in healthy volunteers with Cmax of alcohol in the blood on average 0.08‰ (80 mg/DL).

In patients with hypertension, no signs of interaction of Vega Extra 120 Mg (100 mg) with amlodipine were found. The average additional reduction in blood PRESSURE in the supine position is 8 mm Hg.V. (systolic) and 7 mm Hg.V. (diastolic).

The use of Vega Extra 120 Mg in combination with antihypertensive agents does not lead to additional side effects.

Dosage and administration

Inside, can be taken with or without water. When taking the drug, you should put a tablet, dispersed in the oral cavity, on the tongue, after which it will quickly dissolve, and it can be swallowed. The tablet should be taken immediately after opening the blister. Patients who are recommended a dose of Vega Extra 120 Mg 100 mg, the second tablet of Vega Extra 120 Mg 50 mg should be taken after complete dissolution of the first tablet.

The recommended dose for most adult patients is 50 mg approximately 1 hour before sexual activity. Taking into account the effectiveness and tolerability of the dose can be increased to 100 mg or reduced to 25 mg (only tablets coated with a film, the appropriate dosage). The maximum recommended dose is 100 mg. Patients who are recommended a dose of Vega Extra 120 Mg 100 mg, it is necessary to take 2 table., dispersible in the oral cavity, dosage 50 mg consecutively one after another. The maximum recommended frequency of use — 1 time per day. It should be borne in mind that the absorption of Vega Extra 120 Mg significantly slows down when used in combination with fatty foods.

Special patient groups

Renal impairment. In mild to moderate renal failure dose adjustment is not required, in severe renal failure (Creatinine CL <30 ml/min) Vegal Extra dose should be reduced to 25 mg.

Hepatic impairment. Since the excretion of Vega Extra 120 Mg is disturbed in patients with liver damage (in particular, cirrhosis), the dose of Vega Extra Cobra 120 should be reduced to 25 mg.

Joint application with other drugs. Joint use with ritonavir is not recommended. In any case, the maximum dose of Vegab Extra under any circumstances should not exceed 25 mg, and the frequency of application — 1 time in 48 h (see "Interaction").

When combined with inhibitors of CYP3A4 isoenzyme (erythromycin, saquinavir, ketoconazole, Itraconazole), the initial dose of Vega Extra 120 Mg should be 25 mg (see "Interaction").

To minimize the risk of postural hypotension in patients taking α-blockers, Vega Extra 120 Mg should be started only after achieving hemodynamic stabilization in these patients. Consideration should also be given to reducing the initial dose of Vega Extra (see special instructions and Interactions).

Old age. Adjustment of the dose of Vega Extra 120 Mg is not required.



Cobra Vega Extra Strong 120 Mg

Reviews

Vega-extra84 out of100 with27 ratings
Vega-extraI like Vega-extra more and more each day because it makes my life a lot easier. Vega-extra is the real deal! It's incredible. Vega-extra is worth much more than I paid.Rating:90 out of100, 72Vega-extraIt's just amazing. Wow what great service, I love it! I don't always clop, but when I do, it's because of Vega-extra.Rating:73 out of100, 72Vega-extraYou guys rock! Vega-extra is the most valuable business resource we have EVER purchased.Rating:93 out of100, 72Vega-extraIt really saves me time and effort. Vega-extra is exactly what our business has been lacking. Buy this now. The best on the net! If you want real marketing that works and effective implementation - Vega-extra's got you covered.Rating:81 out of100, 72Vega-extraI love Vega-extra.Rating:92 out of100, 72Vega-extraI love Vega-extra. Thank You! I could probably go into sales for you.Rating:80 out of100, 72Vega-extraI don't always clop, but when I do, it's because of Vega-extra. I am completely blown away. Vega-extra has really helped our business.Rating:74 out of100, 72Vega-extraReally good. I will refer everyone I know.Rating:92 out of100, 72Vega-extraI love Vega-extra.Rating:99 out of100, 72Vega-extraYou've saved our business!Rating:90 out of100, 72Vega-extraI'm good to go. I like Vega-extra more and more each day because it makes my life a lot easier. Absolutely wonderful! Vega-extra is the real deal!Rating:88 out of100, 72Vega-extraVega-extra is the next killer app. The service was excellent.Rating:78 out of100, 72Vega-extraAbsolutely wonderful! It's exactly what I've been looking for. I like Vega-extra more and more each day because it makes my life a lot easier.Rating:74 out of100, 72Vega-extraYour company is truly upstanding and is behind its product 100%.Rating:97 out of100, 72Vega-extraWe're loving it. Vega-extra should be nominated for service of the year.Rating:97 out of100, 72Vega-extraYou guys rock! Vega-extra saved my business. I have gotten at least 50 times the value from Vega-extra.Rating:78 out of100, 72Vega-extraWe can't understand how we've been living without Vega-extra. It's really wonderful. We were treated like royalty.Rating:93 out of100, 72Vega-extraDefinitely worth the investment.Rating:95 out of100, 72Vega-extraGreat job, I will definitely be ordering again!Rating:83 out of100, 72Vega-extraI made back the purchase price in just 48 hours! We have no regrets! I would gladly pay over 600 dollars for Vega-extra.Rating:72 out of100, 72Vega-extraVega-extra has completely surpassed our expectations. We have no regrets!Rating:73 out of100, 72Vega-extraWe're loving it. It's all good.Rating:81 out of100, 72Vega-extraWe have no regrets! If you aren't sure, always go for Vega-extra. Vega-extra is the most valuable business resource we have EVER purchased.Rating:80 out of100, 72Vega-extraI can't say enough about Vega-extra. Thanks Vega-extra! Since I invested in Vega-extra I made over 100,000 dollars profits.Rating:77 out of100, 72Vega-extraI don't know what else to say. I would like to personally thank you for your outstanding product.Rating:87 out of100, 72Vega-extraIt's incredible. I love Vega-extra. Vega-extra should be nominated for service of the year. Vega-extra was worth a fortune to my company.Rating:74 out of100, 72Vega-extraI like Vega-extra more and more each day because it makes my life a lot easier. It's really wonderful. It's incredible.Rating:80 out of100, 72

Our bestsellers